{"id":910,"date":"2024-06-07T08:00:00","date_gmt":"2024-06-06T23:00:00","guid":{"rendered":"https:\/\/socium.co.jp\/?p=910"},"modified":"2024-06-08T14:40:07","modified_gmt":"2024-06-08T05:40:07","slug":"2024060701","status":"publish","type":"post","link":"https:\/\/socium.co.jp\/ja\/2024\/06\/07\/2024060701\/","title":{"rendered":"\u300c\u30a2\u30f3\u30e1\u30c3\u30c8\u30fb\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30cb\u30fc\u30ba\u300d\u306e\u514b\u670d\u306b\u30c1\u30e3\u30ec\u30f3\u30b8\u3059\u308bAI\u5275\u85ac\u30d9\u30f3\u30c1\u30e3\u30fc \u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e\u306e\u8ad6\u6587\u304cThe Journal of Biomedical Research\u8a8c\u306b\u63b2\u8f09"},"content":{"rendered":"\n<p>\u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u4e2d\u592e\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79 \u5800\u672c\u52dd\u4e45\u3001\u4ee5\u4e0b\u300c\u30bd\u30b7\u30a6\u30e0\u300d\uff09\u306e<br>\u30ea\u30f3\u9178\u5316\u89e3\u6790\u4e8b\u696d\u306b\u95a2\u3059\u308b\u8ad6\u6587\u304c\u3001The Journal of Biomedical Research \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u306e\u3067\u304a\u77e5\u3089\u305b\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5f0a\u793e\u3068\u5357\u4eac\u533b\u79d1\u5927\u5b66\u85ac\u5b66\u9662\uff08\u97d3\u5cf0\u9662\u9577\u3001\u9673\u51ac\u5bc5\u6559\u6388\uff09#1\u3068\u306f\u3001\u72ec\u7acb\u884c\u653f\u6cd5\u4eba\u56fd\u969b\u5354\u529b\u6a5f\u69cb\uff08JICA\uff09\u304c\u652f\u63f4\u3059\u308b\u3001\u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u56fd\u79d1\u5b66\u6280\u8853\u90e8\uff08\u79d1\u6280\u90e8\uff09\u304c\u5b9f\u65bd\u3059\u308b\u300c\u79d1\u6280\u90e8\u65e5\u4e2d\u9023\u643a\u4e8b\u696d\u300d#2(\u7b2c\u4e8c\u56de)\u306b\u63a1\u629e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8ad6\u6587\u306f\u3001\u305d\u306e\u5171\u540c\u4e8b\u696d\u306e\u6210\u679c\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>Katsuhisa Horimoto, Yuki Suyama, Tadamasa Sasaki, Kazuhiko Fukui, Lili Feng, Meiling Sun, Yamin Tang, Yixuan Zhang, Dongyin Chen, Feng Han. Phosphorylated protein chip combined with artificial intelligence tools for precise drug screening. The Journal of Biomedical Research, 2024, 38(3): 195-205. DOI: <a href=\"http:\/\/www.jbr-pub.org.cn\/article\/doi\/10.7555\/JBR.37.20230082?viewType=HTML\" data-type=\"link\" data-id=\"http:\/\/www.jbr-pub.org.cn\/article\/doi\/10.7555\/JBR.37.20230082?viewType=HTML\">10.7555\/JBR.37.20230082<\/a><\/p>\n\n\n\n<p>\u5c1a\u3001\u672c\u8ad6\u6587\u306f\u96d1\u8a8c\u306e\u30ab\u30d0\u30fc\u8ad6\u6587\u306b\u63a1\u629e\u3055\u308c\u3001\u7814\u7a76\u5185\u5bb9\u3092\u8868\u3057\u305f\u30a4\u30e9\u30b9\u30c8\u304c\u96d1\u8a8c\u306e\u8868\u7d19\u3092\u98fe\u3063\u3066\u3044\u307e\u3059\u3002<a href=\"http:\/\/www.jbr-pub.org.cn\/index.htm\">http:\/\/www.jbr-pub.org.cn\/index.htm<\/a><\/p>\n\n\n\n<p>\u307e\u305f\u3001\u672c\u8ad6\u6587\u306f\u5171\u540c\u4e8b\u696d\u306e\u5b66\u8853\u6210\u679c\u306e2\u5831\u76ee\u3068\u306a\u308a\u30011\u5831\u76ee\u306f\u4ee5\u4e0b\u306e\u8ad6\u6587\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>Lili Feng, Xiang Chen, Gang Sheng, Yingchun Li, Yingying Li, Yixuan Zhang, Kun Yao, Zhouyue Wu, Rong Zhang, Takayuki Kiboku, Atsushi Kawasaki, Katsuhisa Horimoto, Yamin Tang, Meiling Sun, Feng Han, and Dongyin Chen. Synthesis and Bioevaluation of 3-(Arylmethylene)indole Derivatives: Discovery of a Novel ALK Modulator with Antiglioblastoma Activities. J. Med. Chem. 2023, 66, 21, 14609\u201314622. <a href=\"https:\/\/doi.org\/10.1021\/acs.jmedchem.3c01090\">https:\/\/doi.org\/10.1021\/acs.jmedchem.3c01090<\/a><\/p>\n\n\n\n<p>\u672c\u4ef6\u306b\u95a2\u3059\u308b\u304a\u554f\u3044\u5408\u308f\u305b\u306f\u3001<br><a href=\"mailto:contact@socium.co.jp\">contact@socium.co.jp<\/a> \u3082\u3057\u304f\u306f\u3001<a href=\"https:\/\/socium.co.jp\/ja\/contact\/\">https:\/\/socium.co.jp\/ja\/contact\/<\/a> \u307e\u3067\u3001\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>#\uff11\u3010\u5357\u4eac\u533b\u79d1\u5927\u5b66\u306b\u3064\u3044\u3066\u3011<br>1934\u5e74\u5275\u7acb\u306e\u300c\u6c5f\u8607\u7701\u7acb\u533b\u653f\u5b66\u9662\u300d\u304c\u524d\u8eab\u30021957\u5e74\u306b\u300c\u5357\u4eac\u533b\u5b66\u9662\u300d\u30011993\u5e74\u306b\u300c\u5357\u4eac\u533b\u79d1\u5927\u5b66\u300d\u306b\u6539\u79f0\u3002\u6c5f\u8607\u7701\u4eba\u6c11\u653f\u5e9c\u306b\u5c5e\u3057\u6559\u80b2\u90e8\u3001\u56fd\u5bb6\u885b\u751f\u8a08\u753b\u751f\u80b2\u59d4\u54e1\u4f1a\u304c\u5171\u540c\u904b\u55b6\u3059\u308b\u5730\u65b9\u91cd\u70b9\u5927\u5b66\u300280\u5e74\u4ee5\u4e0a\u306e\u6b74\u53f2\u3092\u3082\u3064\u83ef\u6771\u5730\u533a\u3067\u6709\u6570\u306e\u533b\u79d1\u5927\u5b66\u3002<br><a 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href=\"https:\/\/www.jica.go.jp\/overseas\/china\/others\/pr\/index.html\">https:\/\/www.jica.go.jp\/overseas\/china\/others\/pr\/index.html<\/a><\/p>\n\n\n\n<p>\u3010\u30ea\u30f3\u9178\u5316\u30d1\u30b9\u30a6\u30a7\u30a4\u89e3\u6790\u3011<br>\u30ea\u30f3\u9178\u5316\u30d1\u30b9\u30a6\u30a7\u30a4\u89e3\u6790Phospho-Totum\uff08\u7279\u8a31\u7b2c6884389\u53f7\uff09\u306f\u3001\u7d30\u80de\u4e2d\u306e\u30ea\u30f3\u9178\u5316\u72b6\u614b\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3059\u308b\u4e16\u754c\u521d\u306e\u30b7\u30b9\u30c6\u30e0\u3002\u30ac\u30e9\u30b9\u30d7\u30ec\u30fc\u30c8\uff08\u30a2\u30ec\u30a4\uff09\u4e0a\u306b\u30b9\u30dd\u30c3\u30c8\u3055\u308c\u305f1,471\u7a2e\u306e\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u57fa\u8cea\uff09\u306b\u3064\u3044\u3066\u3001\u7d30\u80de\u3082\u3057\u304f\u306f\u7d44\u7e54\u306e\u7834\u7815\u6db2\u4e2d\u306e\u30c1\u30ed\u30b7\u30f3\u30ad\u30ca\u30fc\u30bc\u306b\u3088\u308b\u30ea\u30f3\u9178\u5316\u3092\u8a08\u6e2c\u3067\u304d\u308b\u3002\u8a08\u6e2c\u5024\u306f\u3001\u30b7\u30fc\u30e0\u30ec\u30b9\u306b\u8a08\u7b97\u30b7\u30b9\u30c6\u30e0\u306b\u5165\u529b\u3055\u308c\u3001\u5404\u57fa\u8cea\u306e\u30ea\u30f3\u9178\u5316\u306e\u5909\u52d5\u306f\u3082\u3061\u308d\u3093\u3001\u7d30\u80de\u5185\u30ad\u30ca\u30fc\u30bc\u306e\u6d3b\u6027\u5316\u5ea6\u30841471\u7a2e\u306e\u57fa\u8cea\u304c\u69cb\u6210\u3059\u308b231\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30d1\u30b9\u30a6\u30a7\u30a4\u306e\u6d3b\u6027\u5316\u5ea6\u3092\u63a8\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u3010\u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e\u306b\u3064\u3044\u3066\u3011<br>\u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e\u306f\u3001\u30d5\u30a1\u30fc\u30b9\u30c8\u30a4\u30f3\u30af\u30e9\u30b9\u306e\u4f4e\u5206\u5b50\u5316\u5408\u7269\u306e\u5275\u85ac\u3092\u884c\u3046\u5275\u85ac\u30d9\u30f3\u30c1\u30e3\u30fc\u4f01\u696d\u3002\u300c\u85ac\u306e\u306a\u3044\u4eba\u306b\u85ac\u3092\u3001\u85ac\u306e\u52b9\u304b\u306a\u3044\u4eba\u306b\u85ac\u3092\u300d\u3092\u30d3\u30b8\u30e7\u30f3\u306b\u63b2\u3052\u3001\u75be\u75c5\u306b\u82e6\u3057\u3080\u60a3\u8005\u69d8\u306e\u30a2\u30f3\u30e1\u30c3\u30c8\u30fb\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30cb\u30fc\u30ba\u306e\u514b\u670d\u306b\u53d6\u308a\u7d44\u3080\u3002\u72ec\u81ea\u306eAI\u5275\u85ac\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Compound-Eyes\u2122\u3001Drug Saver\u2122\u3001Cyber-Drug-Discovery\u2122\u3092\u7528\u3044\u3066\u3001\u5f93\u6765\u306e\u85ac\u7406\u5b66\u7684\u306a\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u9650\u5b9a\u3055\u308c\u308b\u3053\u3068\u306a\u304f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306a\u3069\u5206\u5b50\u60c5\u5831\u306b\u57fa\u3065\u3044\u305f\u65b0\u5947\u306a\u5275\u85ac\u6a19\u7684\u306e\u63a2\u7d22\u3084\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e\u3092\u884c\u3063\u3066\u3044\u308b\u3002<br>\u73fe\u5728\u3001\u304c\u3093\u3084\u96e3\u75c5\u30fb\u5e0c\u5c11\u75be\u60a3\u306a\u3069\u306e\u958b\u767a\u30dd\u30fc\u30c8\u30d5\u30a9\u30ea\u30aa\u3092\u6240\u6709\u3002\u8a73\u3057\u304f\u306f\u3001\u30bd\u30b7\u30a6\u30e0\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\uff08<a href=\"https:\/\/socium.co.jp\/ja\/\">https:\/\/socium.co.jp\/ja\/<\/a>\uff09\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u3010\u672c\u4ef6\u306b\u95a2\u3059\u308b\u304a\u554f\u3044\u5408\u308f\u305b\u5148&nbsp;\u3011<br>\u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e<br>\u6771\u4eac\u90fd\u6c5f\u6771\u533a\u9752\u6d772-4-7<br>\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6240\u3000\u81e8\u6d77\u526f\u90fd\u5fc3\u30bb\u30f3\u30bf\u30fc\u3000<br>\u30d0\u30a4\u30aa\u30fbIT\u878d\u5408\u7814\u7a76\u68df5\u968e\u30016\u968e\u30017\u968e<br><a href=\"https:\/\/socium.co.jp\/ja\">https:\/\/socium.co.jp\/ja\/<\/a><br>E-mail\uff1a<a href=\"mailto:contact@socium.co.jp\">contact@socium.co.jp<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30bd\u30b7\u30a6\u30e0\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u4e2d\u592e\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79 \u5800\u672c\u52dd\u4e45\u3001\u4ee5\u4e0b\u300c\u30bd\u30b7\u30a6\u30e0\u300d\uff09\u306e\u30ea\u30f3\u9178\u5316\u89e3\u6790\u4e8b\u696d\u306b\u95a2\u3059\u308b\u8ad6\u6587\u304c\u3001The Journal of Biomedical Research \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u306e\u3067\u304a\u77e5\u3089\u305b\u3044\u305f\u3057\u307e [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_themeisle_gutenberg_block_has_review":false,"_locale":"ja","_original_post":"https:\/\/socium.co.jp\/?p=910","footnotes":""},"categories":[3],"tags":[],"class_list":["post-910","post","type-post","status-publish","format-standard","hentry","category-news","ja"],"_links":{"self":[{"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/posts\/910"}],"collection":[{"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/comments?post=910"}],"version-history":[{"count":6,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/posts\/910\/revisions"}],"predecessor-version":[{"id":921,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/posts\/910\/revisions\/921"}],"wp:attachment":[{"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/media?parent=910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/categories?post=910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/socium.co.jp\/wp-json\/wp\/v2\/tags?post=910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}